Bifunctional Fusion PROTEIN
Bifunctional fusion proteins consist of a peptide fused to a monoclonal antibody with the goal of allowing targeted delivery. Bifunctional fusion proteins are a novel class of antibody-cytokine fusion proteins that can potentially improve T-cell function and antitumor immunity.1-3
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1. Strauss J, Heery CR, Schlom J, et al. Clin Cancer Res. 2018;24(6):1287-1295. 2. Shen S, Sckisel G, Sahoo A, et al. Front Immunol. 2020;11:832. doi:10.3389/fimmu.2020.00832. 3. Shen S, Sckisel G, Den Otter D, et al. Poster presented at: Keystone Symposia; March 10-14, 2019; Whistler, BC, Canada. Poster 1006.