Bifunctional Fusion PROTEIN

Bifunctional fusion proteins bind 2 different molecules, resulting in a functional outcome. A subset of bifunctional fusion proteins includes a novel class of antibody-cytokine fusions that can potentially improve T-cell function and antitumor immunity.1,2

Learn more about bifunctional fusion protein targets:
PD-1, IL-21R.

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Visit our resources section for further information on modalities currently under investigation.


1. Shen S, Sckisel G, Sahoo A, et al. Front Immunol. 2020;11:832. doi:10.3389/fimmu.2020.00832. 2. Shen S, Sckisel G, Den Otter D, et al. Poster presented at: Keystone Symposia; March 10–14, 2019; Whistler, BC, Canada. Poster 1006.