DARPin^® TECHNOLOGY

DARPin^® molecules are single-domain or multi-domain engineered ankyrin repeat proteins, with each domain being one-tenth the size of a full antibody and having a constant framework and a variable target binding surface. DARPin^® molecules are derived from natural ankyrin repeat proteins, a class of proteins often found in multi-domain formats. DARPin^® binding domains with high affinity and specificity to a given target can be selected from large libraries (containing around 10¹² individual binding molecules).¹

Multispecific DARPin^® molecules may be designed with the aim of eliciting differentiated biological activity.¹

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DARPin^® is a registered trademark owned by Molecular Partners AG.